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Exosome

Royalty Free License
- All Extended Uses
Included Formats
3ds Max 9

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3D Model Specifications
Product ID:610990
Published:
Geometry:Polygonal
Polygons:100,988
Vertices:50,436
Textures:Yes
Materials:Yes
Rigged:No
Animated:No
UV Mapped:Yes
Unwrapped UVs:Unknown
Artist
TurboSquid Member Since December 2009
Currently sells 525 products
Achievements:
Product Rating
Unrated
Description
This is the hydrophobic structure of a exosome protein. It has been procedurally shaded for a nice organic look. Its ready right out of the box to incorporate into any scientific visualization.

The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein complex capable of degrading various types of RNA (ribonucleic acid) molecules. Exosome complexes are found in both eukaryotic cells and archaea, while in bacteria a simpler complex called the degradosome carries out similar functions.

The core of the exosome contains a six-membered ring structure to which other proteins are attached. In eukaryotic cells, the exosome complex is present in the cytoplasm, nucleus and especially the nucleolus, although different proteins interact with the exosome complex in these compartments regulating the RNA degradation activity of the complex to substrates specific to these cell compartments. Substrates of the exosome include messenger RNA, ribosomal RNA, and many species of small RNAs.

The exosome has an exoribonucleolytic function, meaning it degrades RNA starting at one end (the so-called 3? end in this case), and in eukaryotes also an endoribonucleolytic function, meaning it cleaves RNA at sites within the molecule.

Although no causative relation between the exosome complex and any disease is known, several proteins in the exosome are the target of autoantibodies in patients with specific autoimmune diseases (especially the PM/Scl overlap syndrome) and some antimetabolitic chemotherapies for cancer function by blocking the activity of the exosome.
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